Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

EXECUTIVE DIRECTOR, GLOBAL MARKET ACCESS

Summary

The Executive Director, Global Market Access will serve as a pivotal leader in the commercialization of Ionis’ portfolio, driving market access strategy and execution across therapeutic areas. This individual will provide critical strategic input into clinical and commercial development plans, ensuring that pipeline assets are optimized for global market readiness. In addition to shaping access strategies, the Executive Director will collaborate closely with the U.S. market access team to align global and regional initiatives and play a key role in business development activities, including due diligence efforts.

This position reports to the Senior Vice President of New Product Planning and will lead the development and execution of global market access and pricing strategies, tools, and resources to support optimal access for Ionis’ pipeline products. The Executive Director will ensure that global perspectives are integrated into the access strategy and that pricing and reimbursement considerations are aligned across regions. They will also keep leadership informed of evolving global trends and policy and procedure evolution related to disease pricing and reimbursement. In close collaboration with the HEOR team, this individual will help ensure that clinical trials and health economic research are designed to generate the evidence required for impactful Health Technology Assessment (HTA) and Pricing & Reimbursement (P&R) submissions.

Responsibilities

The Executive Director, Global Market Access will:

• Lead the development of global market access strategies and plans for Ionis’ pipeline products, including the creation of core value propositions, key value messages, and identification of critical evidence requirements.
• Design and implement plans for obtaining scientific advice on clinical development programs to ensure study designs, endpoints, and analyses generate the evidence needed for payer and HTA submissions.
• Formulate and present initial pricing and reimbursement strategies to support optimal P&R outcomes across all target markets.
• Collaborate closely with the HEOR team to ensure alignment between market access needs and health economic research plans for pipeline assets.
• Partner with clinical development and regulatory affairs to incorporate payer- and patient-relevant evidence into clinical development strategies.
• Work cross-functionally with New Product Strategy teams to secure alignment and support for market access strategies that drive pricing, reimbursement, and product utilization.
• Identify and assess global market access risks and opportunities, integrating them into product strategies and reflecting them in Target Product Profiles (TPPs).
• Build and lead a high-performing Global Market Access team, fostering a culture of excellence and continuous development.
• Contribute market access insights to lifecycle management planning across assets at the relevant stage gate in development.
• Support Ionis and partner commercialization efforts, ensuring timely payer engagement and optimal pricing, reimbursement, and coverage for commercial assets.
• Develop and disseminate policies and procedures, as needed, to support efficient, compliant, and strategically aligned pricing and reimbursement submissions.
• Serve as a member of the New Product Planning leadership team and lead other Ionis initiatives as necessary.

Requirements

• Bachelor’s degree in life sciences, a scientific discipline, or a related technical field required
• Advanced degree (e.g., Master’s, PhD, PharmD, or MD) strongly preferred
• Advanced degree in health economics, outcomes research, public health, or health policy is highly desirable
• Proven expertise in global Market Access, with a strong understanding of HEOR for both commercial-stage and pipeline products
• Experience in rare disease, orphan, or ultra-orphan product markets is highly desirable
• Minimum of 7 years of experience in developing and implementing Market Access and HEOR strategies across global markets
• Deep understanding of market access and HTA processes, and how HEOR evidence informs payer decision-making
• In-depth knowledge of healthcare systems and reimbursement landscapes in the U.S. and major EU markets
• Exceptional verbal and written communication skills, with the ability to convey complex concepts clearly and persuasively
• Strong analytical and strategic thinking capabilities
• Excellent project management skills, with a track record of delivering results across multiple initiatives
• Demonstrated ability to build, lead, and develop high-performing teams, and to foster effective cross-functional collaboration
• Experience managing multiple projects across diverse therapeutic areas in a dynamic, fast-paced environment
• Travel required up to 25%

Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position; reference requisition # IONIS003778

Ionis offers an excellent benefits package! Follow this link for more details: Ionis Benefits

Full Benefits Link: https://www.ionis.com/careers/working-at-ionis/#:~:text=our%20employee%20spotlight-,Benefits,-Employees%20are%20rewarded

The pay scale for this position is $251,064 to $308,146

NO PHONE CALLS PLEASE. PRINCIPALS ONLY.

Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.